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Presented for research literature review only Ploemen JH et al

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Stem cell niches may reactivate in cleared tissue Months 1-6+: Gradual tissue remodeling and functional recovery in organs where senescent cell burden was reduced This cascade explains why FOXO4-DRI doesn't produce immediate, obvious effects

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Context map Three evidence layers that answer different questions A rodent ulcer model, a supplier vial listing, and a recovery anecdote are not interchangeable

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