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Common side effects associated with retatrutide consistent with the broader GLP-1 receptor agonist class, as described in the Summary of Product Characteristics (SmPC) for licensed medicines such as Wegovy (semaglutide 2.4 mg) and Mounjaro (tirzepatide) include: Nausea (particularly during dose escalation) Vomiting Diarrhoea or constipation Decreased appetite Injection site reactions such as mild redness or discomfort Increased heart rate , which has been observed with incretin-based therapies These gastrointestinal effects are typically most pronounced when starting treatment or increasing the dose, and they often improve over time as the body adjusts
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Contact your GP if dizziness persists or worsens, and seek immediate medical attention for severe dizziness with loss of consciousness, chest pain, or neurological symptoms
Subcutaneous B12 administration, although promising in select cases such as congenital cobalamin disorders, lacks comprehensive comparative studies against IM and oral routes
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