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Treatment with fisetin reduced intracellular ROS levels, motor neuron loss and improved motor activity and survival rate in three different hSOD1-related mutant models of ALS (Drosophila expressing hSOD1 G 85R, hSOD1 G93A NSC34 cells and transgenic mice hSOD1 G93A ) (Wang et al., 2018) (Table 1)
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The first GLP-1 medication, called Byetta (exenatide) , was approved by the FDA in 2005 for type 2 diabetes
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