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Most patients land somewhere between 5 mg and 15 mg as their maintenance dose 15 mg is the ceiling
On average, you might expect to lose about 10-15% of your body weight over several months
References Mechanism of Action 1-6 Sermorelin acts as an agonist at the GHRH receptor in the anterior pituitary, stimulating somatotroph cells to increase the synthesis and pulsatile release of endogenous growth hormone (GH)
Each effect maps to a specific physiological pathway that is disrupted by GH decline in the perimenopause transition
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