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If youve been taking the medication for a few months and youre not losing weight on Zepbound, it might be time to switch to another option, such as Wegovy (semaglutide) or Saxenda (liraglutide)

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slowed gastric emptying (gastroparesis) GLP-1 agonists stimulate GLP-1 receptors in the CNS including vagal efferent fibers in the brainstem

When combined, those risks are compounded in ways that cannot be predicted without rigorous clinical study