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However, the onset of severe upper and middle abdominal pain in conjunction with these symptoms necessitates immediate medical attention, as it could signal pancreatitis
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Treatment with liraglutide at variable doses (0.9 mg to 1.8 mg daily) has been reported in case reports of patients with PWS and concomitant diabetes, showing heterogenous efficacy in BMI reduction from 1.3 kg/m 2 to 11.3 kg/m 2 (3135), waist circumference reduction from 7 to 8 cm (32, 35), as well as HbA1c reduction from 1.9% to 6.5% (3134)
The mechanism of action involves mimicking the naturally occurring hormone GLP-1, which is released from the intestine after eating
