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It will often be prescribed with the intention of being a long-term medication if the patient responds well and is able to continue increasing the dosage until it is maximized

New insights into the pathogenesis of cystic fibrosis: pivotal role of glutathione system dysfunction and implications for therapy

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Tryptase is one of the most common mediators released by mast cells in those with mastocytosis (abnormal numbers of mast cells), but not for those with MCAS (abnormal release of proinflammatory mediators by mast cells, but not an increased number, as in the much rarer mastocytosis)