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The role of glutathione-S-transferase in anti-cancer drug resistance
Additionally, BCL2-inhibitors have been shown to have senolytic effects in some senescent cell models 1,4
doi: 10.1074/jbc.M110.143008 45 Kostoglou-AthanassiouINtallesK
In preclinical models this raises intracellular NAD and SAM, lowers 1-methylnicotinamide, and suppresses fat-cell lipogenesis, which is the proposed basis for the weight and adiposity reductions seen in obese mice
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