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In individual cases where insulin therapy was discontinued due to insulin allergy (41) or cognitive decline (42), treatment with GLP-1 RAs (liraglutide and dulaglutide, respectively) successfully achieved satisfactory glycaemic control (41, 42)
The GSTF8 gene was also induced by H 2 O 2 through the activation of MPK3/MPK6 kinases (Kovtun et al., 2000) the promoter of which contains an as-1 motif, which is implicated in response to oxidative stress (Garretn et al., 2002)
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NAFLD is primarily associated with metabolic risk factors, such as obesity, type 2 diabetes, high cholesterol, and metabolic syndrome
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