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For type 2 diabetes, your options include: DPP-4 inhibitors GLP-1 receptor agonists (Ozempic, Trulicity, Victoza) GLP-1/GIP receptor agonists (Mounjaro) SGLT2 inhibitors Thiazolidinediones And prescription weight-loss medications that are currently available include: Orforglipron, an oral small-molecule non-peptide GLP-1 receptor agonist ( Foundayo ) GLP-1/GIP receptor agonists ( Zepbound ) Phentermine-topiramate ( Qsymia ) Bupropion-naltrexone ( Contrave ) Your clinician, like those through Weight Watchers Med+ , can go over your available options and, if you qualify, prescribe medication and a lifestyle plan designed for your body and your goals.* Retatrutide warnings and precautions Despite the fact that retatrutide is not an approved medication, there is active marketing for medications being characterized as retatrutide. Because retatrutide is still investigational, there is no regulated manufacturing or supply chain, meaning you cannot be sure what you are actually receiving and putting in your body, says Rhodes

Specifically, the progressive loss of behavioral control, manifested by persistent overconsumption despite adverse consequences, mirrors the sustained positive energy balance that underlies and perpetuates weight gain (O'Connor and Kenny, 2022
In a clinical trial of individuals with obesity (but without diabetes), the average weight loss was 7.5%11.2% in 72 weeks