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GSH replenishment in human tissues is difficult due to its shorter half-life, and not easy to penetrate the plasma membrane hence use of prodrugs/precursors such as cysteine, and glycine is the most promising approach 4,45
Tosh SM, Bordenave N
Research in the Journal of Clinical Endocrinology & Metabolism has shown that sustained GH elevation even modest increases significantly impacts visceral fat reduction and lean mass preservation in adults with age-related GH decline (Rudman et al., 1990, NEJM )
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