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Stacked Protocol (AOD + MOTS-c) Dose: 0.5 mg AOD + 10 mg MOTS-c (= 20 clicks) Duration: 4 weeks Frequency: Daily Cycle Interval: Optional 2-week pause Goal / Description: 2 weeks off, then repeat or switch to MOTS-c only maintenance Possible Side Effects AOD-9604 is generally well-tolerated in research settings

References 1 AbdullahL.EvansJ

superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), glutathione S-transferase (GST), -glutamyltransferase (-GT), carnitine palmitoyltransferase 1 (CPT-1), lactate dehydrogenase (LDH), heme oxygenase-1 (HO-1), xanthine oxidase (XO)

57.1%, p = 0.10)