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Monitoring renal function and maintaining adequate hydration during treatment initiation and dose escalation helps prevent dehydration-related complications

Protein goes to the upper end of the range, closer to 1.0 to 1.2 grams per pound of goal body weight, because appetite suppression makes falling short far more likely

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Although the complete repertoire of the gut microbiota remains unrevealed, more than 500 species are estimated to reside in the GI tract (Reference Almeida, Mitchell and Boland138)