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For example, the tumor-inhibitory functions of inflammasomes containing NLRP6, one of the most abundantly expressed PRRs in the colon, include maintaining epithelial barrier integrity through intestinal epithelium self-renewal

16,51 The anxiolytic effect of GLP-1 agonists has been hypothesized due to the preservation of brain-derived neurotrophic factor/nuclear factor erythroid 2related factor 2 levels, decreased oxidative stress, and lipocalin 2 levels in the hippocampus

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A study by Zhang et al