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Acetyl-CoA enters the cycle after either oxidative breakdown of lipids within the mitochondria or after conversion of pyruvate, generated from glycolysis in the cytosol, by the mitochondrial pyruvate dehydrogenase complex
Most side effects are reversible upon discontinuation of therapy, but serious reactions necessitate prompt evaluation and supportive care
Rhs.org.uk
Deeper, bigger changes like reduced pigmentation, improved skin tone, and stronger immunity typically show up around the 6 to 8-week mark
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