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It is also prescribed in cases where the deficiency is because of secondary complications of some inborn metabolic errors including fatty acid oxidation defects and organic acidaemias

Similarly, several novel MCT1/4 inhibitors are under investigation, including AZD3965, which has demonstrated anti-tumor effects by inhibiting MCT1, disrupting lactate metabolism in tumors, and causing lactate accumulation within cancer cells

This review highlights methionine as a critical amino acid in cellular and metabolic health, demonstrating that both restriction and supplementation can influence lifespan, inflammation, and metabolic function, with optimal dosing essential to balance benefits and risks