With over 14 years of clinical trial data and 7 years of real-world use, semaglutide represents one of the more thoroughly studied medications in its class, though it's important to recognize that very long-term data (beyond 57 years of continuous use) remains limited
In addition to these favorable features, semaglutide, similarly to other GLP-1 RAs, offers beneficial effects on cardio-vascular (CV), renal, and liver protection, making this molecule an advantageous choice in the therapeutic management of diabesity (coexistence of both diabetes and obesity) and its co-morbidity
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Concerning food choices, a low-fat diet with meals prepared by boiling, baking, or grilling is crucial for a better management of GI AEs [15]