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The opposing effects of cannabinoids (either improving or worsening intestinal permeability) might be related to the recent observation that endocannabinoids such as anandamide worsen permeability while phytocannabinoids like cannabidiol and tetrahydrocannabidiol, which might act as (partial) CB1R antagonists, promote protection or recovery from intestinal permeability [52]

Subcutaneous infections from poor hygiene are rare but entirely preventable

If signs of vitamin B12 toxicity are observed, its essential to seek immediate medical attention at the nearest healthcare facility for prompt treatment

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