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When the NLRP3 inflammasome is activated, it activates caspase-1, which then forms active forms of pro-inflammatory cytokines such as IL-1 and IL-18 [186]

For management strategies, see our semaglutide side effects guide

Patients who had metabolic bariatric surgery at a large US health system between 2010 and 2017 were compared to nonsurgical patients who continuously received GLP-1RA