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Multivalent interactions of the disordered regions of XLF and XRCC4 foster robust cellular NHEJ and drive the formation of ligation-boosting condensates in vitro
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Hepatology 17 , 131142 (1993)
Specifically, we observed a stacked, filament-like architecture in which only WD40 domains of COP1 in the top layer are accessible, and a substrate-accessible dimeric architecture that is favored upon co-expression of c-Jun or ETS2
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