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A guide to collect and combine multi-omics data was recently published by Athieniti and Spyrou in (Athieniti and Spyrou, 2023) and a comprehensive review of integrative methods and associated statistical methodologies by Vahabi and Michailidis can be found here (Vahabi and Michailidis, 2022)
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Its biochemical properties have been investigated in cellular, tissue and animal models, while human evidence for intranasal use remains insufficient for establishing clinical benefits, pharmacokinetics or long-term safety
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