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These regenerative and protective actions lead to longevity and longer healthspan
FOXO4-DRI was designed as a competitive interference peptide: a retro-inverso analogue of the FOXO4 region implicated in that contact, joined to a cell-penetrating import segment so the construct can reach the nuclear compartment in cell models
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Expanding that framework, or developing alternatives that achieve similar outcomes for the commercially insured population, will require policy innovation that moves faster than the current rate of change
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