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Unlike weight loss, which shrinks fat cells but does not remove them, fat dissolvers permanently destroy targeted fat cells, preventing them from accumulating fat in the future
GLP-1 medications became popular because they can affect hunger, fullness, digestion, cravings, and blood sugar signaling in a more direct medical way
Since patients with HF with New York Heart Association class IV were excluded from the CVOTs, it is unclear whether safety risks could occur in semaglutide-treated patients
However, significant risks and limitations must be considered
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