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NADPH oxidases (NOXs) are major sources of intracellular ROS 54 , while heme oxygenase-1 (HO-1, encoded by HMOX1 ) and NAD(P)H quinone dehydrogenase 1 (NQO1) play pivotal roles in countering oxidative stress and ferroptosis 55,56
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These benefits are valuable as chronic inflammation and oxidative damage have been linked to aging and reduced tissue repair
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