The average baseline characteristics in the trial included 71 % women, 42 % of hypertensive patients, 19 % with type 2 diabetes mellitus, 28 % with a body mass index greater than 40 kg/m2 corresponding to obesity, and 4 % with cardiovascular conditions
2,9,10 At the start of oral vitamin B12 replacement therapy, close monthly monitoring of laboratory results and symptoms is recommended, thereafter annual monitoring should suffice
Methods Protocol and registration No ethical approval was required as the current study involved analyzing and synthesizing previously published data and information from secondary use of deidentified electronic databases (Code of Federal Regulations, 45 CFR 46.102)
Luo, B., Ma, Y., Zhou, Y., Zhang, N