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In clinical trials, constipation rates with cagrilintide ranged from approximately 10% to 25% depending on the dose, compared to roughly 5% to 8% with placebo
Diarrhea: Intestinal transit can become irregular or accelerated in some patients, leading to diarrhea that is typically mild to moderate and temporary
This is exactly why the reconstitution chart matters so much for split dosing
The decrease in GnRH is due to the increased secretion of CRH.16 On the other hand, an increase in LH, testosterone due to metabolic disorders in the body can cause infertility due to ovulation abnormalities
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