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A 6 cm central zone was left clear of bedding to serve as the starting area
To view or add a comment, sign in How to individualize renoprotective therapy in obese patients with chronic kidney disease: a commentary by the Diabesity Working Group of the ERA Open Access Nephrology Dialysis Transplantation, Volume 40, Issue 10, October 2025, Pages 19771988, Published: 13 May 2025 The interrelated pandemics of obesity and type 2 diabetes mellitus (T2DM) are fuelling an increase in the prevalence of chronic kidney disease (CKD), which amplifies the risk of cardiovascular events and may progress to end-stage kidney disease (ESKD)
The STEP-1 extension trial followed patients who had lost weight on semaglutide and then switched to placebo
Older adults (60+) May benefit from extended escalation intervals (6 weeks per step instead of 4) due to: Slower metabolic adaptation Increased medication sensitivity Higher likelihood of comorbid conditions Potential polypharmacy interactions Body Weight and Composition Factors Unlike some medications dosed per kilogram of body weight, cagrilintide uses fixed dosing regardless of baseline weight
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