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If you have a personal or family history of certain conditions, such as pancreatitis or medullary thyroid carcinoma, or are pregnant or breastfeeding, this treatment approach is not recommended for you
However, strong inhibitors of CYP3A (e.g., itraconazole, clarithromycin) may increase the plasma concentrations of amlodipine to a greater extent [see Drug Interactions ( 7.1)]
It is essential to ensure that you are getting enough of it
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