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For example, a person with FTO variants associated with elevated appetite drive and lower baseline satiety signaling might benefit from aggressive GLP-1 therapy, while a patient with MC4R mutations affecting metabolic rate could see added value in growth hormone support for basal metabolic enhancement

| doi:10.1113/jphysiol.2010.201343 Wolf G: The discovery of a vitamin role for carnitine: The first 50 years

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