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What are Rybelsus and Ozempic

These medications help regulate blood sugar by increasing insulin secretion and reducing the release of glucagon

Methods: We included 239 PWIDs on OAT starting DOT with DAAs 03/2020-10/2022 ("COVID" period), and a control group of 441 PWIDs receiving DOT 09/2014-03/2020 ("pre-COVID" period)

Safety Considerations and Future Outlook As with all pharmacotherapy for obesity and T2D, establishing cardiovascular safety and demonstrating improvements in meaningful clinical outcomes will be essential, particularly as cardiovascular outcome trials have not yet been completed with multi-agonists (although data are expected soon for tirzepatide: SURPASS-CVOT [T2D] in 2025