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We extracted baseline weight and BMI immediately before the initiation of the GLP-1based therapy (closest to the baseline 24-hour urine collection) and furthest follow-up weight and BMI while on GLP-1based therapy (closest to the follow-up 24-hour urine collection)
There is also some limited evidence suggesting that individuals who carry certain polymorphisms in genes involved in vitamin C transport and detoxification mechanisms may have lower plasma vitamin C concentrations even with high vitamin C intakes (see also Vascular complications of diabetes mellitus) (reviewed in 27)
While IGF-1 LR3 offers potential benefits for muscle, metabolism, and even skin health, it also carries significant risks that clinicians must discuss with patients
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