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By way of review, androgenic alopecia (AA) is frequently associated with metabolic disorders including insulin resistance and obesity, leading to significant interest in potential therapeutic interactions
Skin Penetration and Depot Formation An ex vivo human skin penetration study measured a permeability coefficient of 2.43 x 10^-4 cm/h for copper tripeptide, with 82 micrograms per square centimeter retained in dermal tissue as a depot over 48 hours (PMID 20703511)
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Theoretically, a low S-5-HT value would be expected to result from lack of its precursor tryptophan or disturbance in the two-step synthesis described above
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