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The proposed mechanism includes modulation of oxidative stress and mitochondrial biogenesis
However, symptoms such as nausea, reflux, bloating, burping, abdominal discomfort or diarrhoea may disturb sleep, especially if they happen after eating late or lying down soon after a meal
There's also been a tremendous surge (more than 1,000% increase) in GLP-1 overdoses or side effects since 2021, according to the National Poison Data System from America's Poison Centers
Recently, Altimmune reported interim data for its weekly injectable GLP-1/glucagon dual agonist (pemvidutide) in a Phase 2 trial--disappointing levels of discontinuations sent the stock tumbling 55%
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