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Weight Loss Plateaus: Plateau Statistics: Weight loss may plateau after about a year of taking semaglutide, which is a normal part of the weight loss process
Mild injection-site irritation or localized inflammation
9 Weight cycling increases the risk of sarcopenic obesity, a condition in which patients still have obesity but also a reduction in skeletal muscle mass and function
Of the licensed options, Mounjaro currently produces the largest average weight loss and is the closest available comparator to retatrutide, sharing two of its three receptor targets
![Retatrutide + Cagrilintide: The Weight Loss Stack Outperforming Ozempic [2026 Protocol]](https://levamedical.com/hs-fs/hubfs/image-png-4.png?width=1218&height=537&name=image-png-4.png)
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