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This prolonged retention increases pressure, fullness, and discomfort, especially after larger, protein-dense, or high-fat meals, even though digestion continues normally and food is not physically blocked. Large meal volume and gastric distension Larger meal volumes cause the stomach to stretch

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In the human study, researchers analyzed transferrin saturation in 130 patients with epilepsy compared to 128 sex- and age-matched control subjects without epilepsy to investigate whether iron overload is a predisposing factor for epilepsy

Cell 168 , 960976 (2017)