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doi:10.1007/s00441-019-03016-8 Mayfield CK, Bolia IK, Feingold CL, et al
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An unbiased genome-wide siRNA screen for suppressors of ferroptosis found that loss of cysteinyl-tRNA synthetase (CARS) increases cystathionine and activates the transsulfuration pathway to suppress ferroptosis, which is induced by the well-known system ( SLC7A11 ) inhibitor, erastin (Table 1) (Hayano et al., 2016)
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