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& Budanov, A
This imbalance did not affect the primary endpoint and the incidence rate was higher in patients with a previous history of heart failure and independent of renal function at study baseline (57, 66, 67)
Eli Lilly reported dysesthesia was "generally mild" and "rarely led to discontinuation." TRIUMPH-1 the larger general obesity trial with 2,339 patients at 80 weeks confirmed dysesthesia at 12.5% on the 12mg dose, substantially lower than TRIUMPH-4's 20.9%
They may include flushing, slight nasal irritation, headaches, or mild nausea
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