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The most effective approach addresses both layers: BHRT restores the hormonal foundation, and targeted peptide therapy optimizes the systems that hormones alone dont fully restore
Research is ongoing about the link between these meds and mental health
Upon release, Nrf2 translocates to the nucleus where it can bind to the antioxidant response element (ARE) located in the promoter region of genes coding for antioxidant enzymes and scavengers
Inhibitors for these abovementioned protein targets have entered clinical trials ( Figure 1 )
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