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reported that cleavage products derived from GLP-1 reduced tubulointerstitial renal damage, lowered the expression of tubular injury markers, and attenuated the renal accumulation of macrophages and T cells ( Glycemic Control Although the glucose-independent mechanisms are emphasized, glycemic control by GLP-1RAs is considered to be involved in its renoprotective effects
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These studies have measured both safety and efficacy across key biomarkers related to appetite regulation, metabolic function, and nutrient absorption
An independent team evaluated the efficacy and safety profile of monotherapy and combination groups during this interim analysis for internal decision-making
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