( a ) Fasting plasma GIP (CON n = 11, Gipr AP-KO n = 12), ( b ) total GLP-1 (CON n = 11, Gipr AP-KO n = 12) ( c ) insulin (CON n = 11, Gipr AP-KO n = 12), ( d ) food intake post IPGTT, ( e ) ad lib fed blood glucose, ( f ) RER, ( g ) energy expenditure (inset, with ANCOVA using BW as covariate), ( h ) ambulatory activity (x beam breaks) of std chow fed (lean) mice ( d - h : CON n = 11, Gipr AP-KO n = 13, symbols as defined in f)
Recognising the link between tiredness and vitamin B12 deficiency is crucial, as early diagnosis and treatment can prevent serious, potentially irreversible neurological complications whilst restoring energy levels and overall wellbeing
The follow-up blood test tells me whether the chosen approach is working
They will monitor you throughout your treatment