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Abdel-Mageed HM, AbuelEzz NZ, Radwan RA, Mohamed SA
Checklist for adherence: baseline labs, informed consent, dosing log, adverse event log, follow-up schedule, and stop criteria
High-performance liquid chromatography quantification of GSH/GSSG, 3-NT and 3-CT To evaluate biomarkers of oxidative stress and damage by high-performance liquid chromatography (HPLC), approximately 200 mg of tissue was minced and homogenized in 500 l of ice-cold phosphate-buffered saline
A systematic review of 35 studies found consistent age-related GSH decline in blood and specific brain regions, including the precuneus, hippocampus, cingulate, and frontal cortex
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