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Primary metabolism of aflatoxin B 1 Once inside the body and for toxicity to occur, AFB 1 undergoes enzymatic conversion to electrophilic endo and exo stereoisomers of AFB 1 -8,9-epoxide by the action of mixed function mono-oxygenase enzyme systems, CYPs are an intensively studied family of enzymes with currently approximately 4,000 known members

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