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Morningstar assigns Novo a 5-star rating, compared with 2 stars for rival Lilly
Enrollment, follow-up, data analysis, NDA (New Drug Application) preparation, and FDA review typically add up to 18-36 months even with Breakthrough Therapy Designation, which Lilly has received for retatrutide in obesity
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To examine the similarity of peptides predicted by different models within each potency profile, we used PCA, considering the 500 one-hot-encoded sequences generated across all five compared models, the wild-type peptideshGCG and hGLP-1and their single-step mutants (551 hGCG and 570 hGLP-1), such that the projection was computed for an array [1,621 21 L ]
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