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It is not clear whether the replacement of melanocytes of the basal cell layer of the oral epithelium lost to physiological processes of apoptosis or senescence, or to mechanical, thermal, or chemical injury is the result of cell division of mature melanocytes in the basal cell layer of the oral epithelium which still retain their capacity of replication, or a result of migration from their local niche reservoirs of melanocyte stem/progenitor cells and their subsequent proliferation [6]
Weight-loss outcome assumptions (15% average reduction in body weight over 12 months) were based on results from the STEP 1 and SURMOUNT 1 clinical trials
Atypical pigmented lesions that are reported to be of recent or acquired onset in the nonpediatric population sometimes display features of a benign congenital melanocytic nevus
Protective effects of metallothionein on streptozotocin-induced diabetes in rats
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