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A federal pharmacy-PBM separation mandate would redirect specialty pharmacy volume away from Accredo, CVS Specialty, and OptumRx Specialty, creating market access opportunity for non-affiliated specialty pharmacies
GLP-1 is a clinically validated target, thus less development risk than a first-in-class target
In animal studies, GLP-1 receptor agonists like semaglutide have been associated with thyroid C-cell tumors, although the relevance to humans remains unclear, thus requiring monitoring for thyroid abnormalities (Davies et al., 2021)
Nitric Oxide Biol Chem 78:7280
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