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As there is no meaningful expression of GLP-1 receptors on hepatocytes, the major effect of GLP-1 agonists on MASH is likely to be indirect and may be related to a reduction in calorie intake, body weight and insulin resistance, all of which would lead to reduced liver lipid accumulation and hepatic inflammation 7,8
Contrave for Weight Loss: What You Need to Know Contrave is an FDA-approved prescription weight loss medication that combines two active ingredients, naltrexone and bupropion, to help reduce appetite and control food cravings
