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To determine whether tamoxifen could inhibit the activity of UGT2B7 in a time-dependent inhibition manner, tamoxifen with a final concentration (0 M / 6.25 M / 12.5 M / 25 M / 50 M / 100 M) was pre-incubated with HLMs (0.1 mg/ml) system including 50 mM Tris-HCl buffer (pH 7.4), 3 mM UDPGA and 25 g/ml alamethicin for 0 / 15 / 30 / 45 / 60 min at 37 C
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"FDA Approves Wegovy for Cardiovascular Risk Reduction." FDA.gov Novo Nordisk
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