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Some side effects of Varenicline include: Nausea Inflammation of the nose and throat Abnormal dreams Difficulty sleeping Headache Skin rash, itching Chest infection For a full list of side effects, refer to the patient information leaflet
Glycemic mechanism and insulin sparing sensitization not secretion: fasting insulin and C-peptide fall while insulin sensitivity (HOMA2-%S) rises +31.8/+43.2/+49.9% (SURPASS J-mono, Hamamoto 2025)
Sleep apnea, fragmented sleep, alcohol-related sleep disruption, circadian instability, and chronic under-recovery deserve attention in any serious brain-health plan
Healthcare providers are increasingly focusing on monitoring body composition changes rather than just weight loss numbers, as maintaining muscle mass is crucial for long-term health outcomes
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