2.4 Sample size calculation The study was designed to include 16 eyes (8 in each group), providing a 95% statistical power to detect a significant difference between the hyaluronic acid + glutathione group and the hyaluronic acid-only group, assuming a 20% dispersion index and a two-sided = 0.05 ( 2.5 Study procedures All tests and data collection were performed by a cornea specialist
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SodiumGlucose Cotransporter Inhibitors Function of SodiumGlucose Cotransporters in the Human Body Sodiumglucose cotransporter-2 (SGLT2) is a high-capacity, low-affinity transporter located solely in the luminal membrane of the S1 and S2 segments of the proximal convoluted tubule of nephrons, and they are responsible for about 90% of renal glucose reabsorption
Nuclear receptors constitute a superfamily of ligand-activated transcription factors, which regulate critical physiological processes including growth, development, hormonal signals, reproduction, and energy metabolism (Sonoda et al., 2008)