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It is provided exclusively for in vitro laboratory research in qualified experimental settings
Which formulations, if any, carry higher rates of specific adverse events
Cons: Not FDA-approved for any indication, and as of an October 2023 FDA action, ineligible for legal compounding for human use, so supply is limited to research-use-only sellers with variable purity and quality control
For example, -glucans from fungi can activate initiator caspase-8 and effector caspase-3, leading to mitochondrial cytochrome C release and apoptosis in cancer cells (132)
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